Cardiovascular function during acute normovolemic hemodilution (ANH) with hydroxyethyl starch or Ringer's lactate

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Hemodynamic compensation during acute normovolemic hemodilution.

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

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Hemodynamic Compensation during Acute Normovolemic Hemodilution

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

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Effect of high- and low-molecular-weight low-substituted hydroxyethyl starch on blood coagulation during acute normovolemic hemodilution in pigs.

BACKGROUND Hydroxyethyl starches (HES) with lower impact on blood coagulation but longer intravascular persistence are of clinical interest. The current study aimed to investigate in vivo the isolated effect of molecular weight on blood coagulation during progressive acute normovolemic hemodilution. METHODS Twenty-four pigs were normovolemically hemodiluted up to a total exchange of 50 ml . k...

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Acute decrease in renal microvascular PO2 during acute normovolemic hemodilution.

Large differences in the tolerance of organ systems to conditions of decreased O(2) delivery such as hemodilution exist. The kidney receives approximately 25% of the cardiac output and O(2) delivery is in excess of the oxygen demand under normal circumstances. In a rat model of acute normovolemic hemodilution (ANH), we studied the effect of reduced hematocrit on renal regional and microvascular...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2001

ISSN: 1364-8535

DOI: 10.1186/cc1356